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Abnova
MARCH5 Monoclonal Antibody (3C3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00054708-M06
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C3
抗原
MARCH5 (NP_060294.1, 1 a.a. approximately 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.32 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MPDQALQQML DRSCWVCFAT DEDDRTAEWV RPCRCRGSTK WVHQACLQRW VDEKQRGNST ARVACPQCNA EYLIVFPKLG PVVYVLDLAD RLISK
靶标信息
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase MARCH5; membrane associated ring finger 5; membrane-associated ring finger (C3HC4) 5; membrane-associated RING finger protein 5; membrane-associated RING-CH protein V; mitochondrial ubiquitin ligase; ring finger protein 153; RING-type E3 ubiquitin transferase MARCH5; RING-type E3 ubiquitin transferase MARCHF5; unnamed protein product
基因别名: MARCH-V; MARCH5; MITOL; RNF153
UniProt ID: (Human) Q9NX47
Entrez Gene ID: (Human) 54708
protein polyubiquitination
protein ubiquitination
negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
protein K27-linked ubiquitination
protein autoubiquitination
protein K63-linked ubiquitination
protein localization to mitochondrion
protein K48-linked ubiquitination
regulation of mitochondrial fission
positive regulation of mitochondrial fission
positive regulation of cGAS/STING signaling pathway
positive regulation of NLRP3 inflammasome complex assembly
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