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Abnova
MARVELD1 Polyclonal Antibody, MaxPab™
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Product Details
H00083742-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MARVELD1 (NP_113672.1, 1 a.a. approximately 173 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLPPPPRQPP PQARAARGAV RLQRPFLRSP LGVLRLLQLL AGAAFWITIA TSKYQGPVHF ALFVSVLFWL LTLGLYFLTL LGKHELVPVL GSRWLMVNVA HDVLAAALYG AATGIMSDQM QRHSYCNLKD YPLPCAYHAF LAAAVCGGVC HGLYLLSALY GCGRRCQGKQ EVA
Target Information
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MARVEL (membrane-associating) domain containing 1; MARVEL domain-containing protein 1; putative MARVEL domain-containing protein 1; RP11-548K23.8
Gene Aliases: bA548K23.8; GB14; MARVD1; MARVELD1; MRVLDC1
UniProt ID: (Human) Q9BSK0
Entrez Gene ID: (Human) 83742
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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