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MA5-15553 targets MATK in indirect ELISA, FACS and WB applications and shows reactivity with Human samples.
The MA5-15553 immunogen is purified recombinant fragment of human MATK expressed in E. Coli.
MA5-15553 detects MATK which has a predicted molecular weight of approximately 56kDa.
MATK (Hyl) is a non-receptor CSK-type protein tyrosine kinase that is thought to function in signal transduction pathways important in megakaryocyte growth and/or differentiation. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CHK; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; DKFZp434N1212; Hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; HYL tyrosine kinase; leukocyte carboxyl-terminal src kinase related; Megakaryocyte-associated tyrosine-protein kinase; MGC1708; MGC2101; Protein kinase HYL; tyrosine kinase MATK; Tyrosine-protein kinase CTK; tyrosylprotein kinase
基因别名: CHK; CTK; HHYLTK; HYL; HYLTK; Lsk; MATK
UniProt ID: (Human) P42679
Entrez Gene ID: (Human) 4145