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Antibody detects endogenous levels of total MC2R.
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins are peptides derived from pro-opiomelanocortin. MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ACTH receptor; Adrenocorticotropic hormone receptor; Adrenocorticotropin receptor; corticotropin receptor; MC2 receptor; MC2-R; melanocortin 2 receptor (adrenocorticotropic hormone); Melanocortin receptor 2; MGC125798
基因别名: ACTH-R; ACTHR; MC2-R; MC2R
UniProt ID: (Human) Q01718, (Mouse) Q64326
Entrez Gene ID: (Human) 4158, (Mouse) 17200, (Rat) 282839