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Fabgennix
MC3 Receptor Polyclonal Antibody
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Product Details
MC3R-321AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequences on MC3r protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MC3 receptor; MC3-R; Melanocortin receptor 3; obesity quantitative trait locus
Gene Aliases: BMIQ9; MC3; MC3-R; MC3R; OB20; OQTL
UniProt ID: (Human) P41968, (Mouse) P33033, (Rat) P32244
Entrez Gene ID: (Human) 4159, (Mouse) 17201, (Rat) 29310
regulation of heart rate
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
regulation of blood pressure
positive regulation of cAMP biosynthetic process
circadian regulation of gene expression
homoiothermy
locomotor rhythm
sodium ion homeostasis
regulation of feeding behavior
signal transduction
G-protein coupled receptor signaling pathway
rhythmic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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