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Invitrogen
MCCC2 Polyclonal Antibody
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MCCC2 Antibody (PA5-96888) in WB
Western blot analysis of MCCC2 in extracts of various cell lines. Samples were incubated with MCCC2 Polyclonal antibody (Product # PA5-96888) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-96888
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_0714151)
偶联物
形式
Liquid
浓度
2.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LHLTRKVVRN LNYQKKLDVT IEPSEEPLFP ADELYGIVGA NLKRSFDVRE VIARIVDGSR FTEFKAFYGD TLVTGFARIF GYPVGIVGNN GVLFSESAKK GTHFVQLCCQ RNIPLLFLQN ITGFMVGREY EAEGIAKDGA KMVAAVACAQ VPKITLIIGG SYGAGNYGMC GRAYSPRFLY IWPNARISVM GGEQAANVLA TITKDQRARE GKQFSSADEA ALKEPIIKKF EEEGNPYYSS ARVWDDGIID PADTRLVLGL SFSAALNAPI EKTDFGIFRM; Positive Samples: HeLa, HepG2, K562, U-251MG, mouse liver, mouse kidney, mouse heart, rat brain, rat kidney, MCF7, 22Rv1, Mouse liver, Mouse kidney, Mouse heart, Rat brain; Cellular Location: Mitochondrion matrix
靶标信息
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; biotin carboxylase; MCCase subunit beta; meth; methylcrotonoyl-CoA carboxylase 2 (beta); Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; testicular secretory protein Li 29
基因别名: 4930552N12Rik; MCCB; MCCC2
UniProt ID: (Human) Q9HCC0, (Rat) Q5XIT9, (Mouse) Q3ULD5
Entrez Gene ID: (Human) 64087, (Rat) 361884, (Mouse) 78038
