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Invitrogen
MCF2 Polyclonal Antibody
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产品信息
PA5-17112
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the amino terminus of human MCF2/Dbl
偶联物
形式
Liquid
浓度
47 µg/mL
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MCF.2 cell line derived transforming sequence; mcf.2 transforming sequence; Oncogene MCF2 (oncogene DBL); OTTHUMP00000024159; Proto-oncogene DBL; Proto-oncogene MCF-2
基因别名: ARHGEF21; B230117G22Rik; DBL; Mcf-2; MCF2; RGD1566098
UniProt ID: (Human) P10911
Entrez Gene ID: (Human) 4168, (Mouse) 109904, (Rat) 317598
