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Abnova
MCM10 Polyclonal Antibody, MaxPab™
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产品信息
H00055388-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MCM10 (NP_060988.3, 1 a.a. approximately 874 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.36 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDEEEDNLSL LTALLEENES ALDCNSEENN FLTRENGEPD AFDELFDADG DGESYTEEAD DGETGETRDE KENLATLFGD MEDLTDEEEV PASQSTENRV LPAPAPRREK TNEELQEELR NLQEQMKALQ EQLKVTTIKQ TASPARLQKS PEKSPRPPLK ERRVQRIQES TCFSAELDVP ALPRTKRVAR TPKASPPDPK SSSSRMTSAP SQPLQTISRN KPSGITRGQI VGTPGSSGET TQPICVEAFS GLRLRRPRVS STEMNKKMTG RKLIRLSQIK EKMAREKLEE IDWVTFGVIL KKVTPQSVNS GKTFSIWKLN DLRDLTQCVS LFLFGEVHKA LWKTEQGTVV GILNANPMKP KDGSEEVCLS IDHPQKVLIM GEALDLGTCK AKKKNGEPCT QTVNLRDCEY CQYHVQAQYK KLSAKRADLQ STFSGGRIPK KFARRGTSLK ERLCQDGFYY GGVSSASYAA SIAAAVAPKK KIQTTLSNLV VKGTNLIIQE TRQKLGIPQK SLSCSEEFKE LMDLPTCGAR NLKQHLAKAT ASGIMGSPKP AIKSISASAL LKQQKQRMLE MRRRKSEEIQ KRFLQSSSEV ESPAVPSSSR QPPAQPPRTG SEFPRLEGAP ATMTPKLGRG VLEGDDVLFY DESPPPRPKL SALAEAKKLA AITKLRAKGQ VLTKTNPNSI KKKQKDPQDI LEVKERVEKN TMFSSQAEDE LEPARKKRRE QLAYLESEEF QKILKAKSKH TGILKEAEAE MQERYFEPLV KKEQMEEKMR NIREVKCRVV TCKTCAYTHF KLLETCVSEQ HEYHWHDGVK RFFKCPCGNR SISLDRLPNK HCSNCGLYKW ERDGMLKEKT GPKIGGETLL PRGEEHAKFL NSLK
靶标信息
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homolog of yeast MCM10; HsMCM10; MCM10 minichromosome maintenance deficient 10; MGC126776; minichromosome maintenance complex component 10; Protein MCM10 homolog
基因别名: CNA43; DNA43; MCM10; PRO2249
UniProt ID: (Human) Q7L590
Entrez Gene ID: (Human) 55388
