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MA1-40039 detects MD-1 from mouse samples.
MA1-40039 has been successfully used in flow cytometry and functional assay applications.
The MA1-40039 immunogen is mouse MD-1 extracellular protein.
Endotoxin level < 24 EU/mg
MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ly-86; Lymphocyte antigen 86; Protein MD-1; RP1-80N2.1
基因别名: Ly86; MD-1; MD1
UniProt ID: (Mouse) O88188
Entrez Gene ID: (Mouse) 17084