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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total ME2.
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Malic enzyme 2; NAD-dependent malic enzyme, mitochondrial; NAD-ME
基因别名: AW120568; D030040L20Rik; ME2; NAD-ME
UniProt ID: (Mouse) Q99KE1
Entrez Gene ID: (Mouse) 107029