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Bethyl Laboratories
MED12 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A300-774A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 2127 and the C-terminus (residue 2177) of human Mediator of RNA Polymerase II Transcription, subunit 12.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee
靶标信息
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator-recruited cofactor 240 kDa component; CAG repeat protein 45; HOPA; human opposite paired; KIAA0192; Kohtalo homolog; mediator of RNA polymerase II transcription, subunit 12 homolog; mopa protein; MOPA-1; OPA-containing protein; OPA-containing protein 1; putative mediator subunit 12; thyroid hormone receptor-associated protein complex 230 kDa component; thyroid hormone receptor-associated protein, 230 kDa subunit; TNRC11; trinucleotide repeat containing 11 (THR-associated protein); trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit); trinucleotide repeat-containing gene 11 protein; unnamed protein product
基因别名: 230kDa; ARC240; CAGH45; FGS1; HDKR; HOPA; Kto; MED12S; Mopa; OHDOX; OKS; OPA-1; OPA1; TNRC11; TRAP230
UniProt ID: (Human) Q93074, (Mouse) A2AGH6
Entrez Gene ID: (Human) 9968, (Mouse) 59024
somitogenesis
neural tube closure
regulation of transcription from RNA polymerase II promoter
endoderm development
heart development
oligodendrocyte development
Schwann cell development
protein ubiquitination
stem cell population maintenance
spinal cord development
neural tube development
post-anal tail morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic organ development
embryonic neurocranium morphogenesis
Wnt signaling pathway, planar cell polarity pathway
positive regulation of transcription initiation from RNA polymerase II promoter
axis elongation involved in somitogenesis
embryonic brain development
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