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Abnova
MEFV Monoclonal Antibody (2C1)
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产品信息
H00004210-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2C1
抗原
MEFV (NP_000234, 1 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP VKMATLLVTY YGEEYAVQLT LQVLRAINQR LLAEELHRAA IQEYSTQENG TDDSAASSSL
靶标信息
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGNC:6998; Marenostrin; MGC126560; MGC126586; Pyrin
基因别名: FMF; MEF; MEFV; TRIM20
UniProt ID: (Human) O15553
Entrez Gene ID: (Human) 4210
inflammatory response
positive regulation of autophagy
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
response to interferon-gamma
negative regulation of inflammatory response
negative regulation of macrophage inflammatory protein 1 alpha production
negative regulation of cytokine production involved in inflammatory response
negative regulation of NLRP3 inflammasome complex assembly
positive regulation of cysteine-type endopeptidase activity
