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Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein with ASARM motif (bone); OF45; Osteoblast/osteocyte factor 45; Osteoregulin
基因别名: Mepe
UniProt ID: (Rat) Q9ES02
Entrez Gene ID: (Rat) 79110