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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: WICKKWFPYF LVRFTVIYNE QMASKKRELF SNLQEFAGPS GKLSLLEVGC GTGANFKFYP PGCRVTCIDP NPNFEKFLIK SIAENRHLQF ERFVVAAGEN MHQVADGSVD VVVCTLVLCS VKNQERILRE VCRVLRPGGA FYFMEHVAAE CSTWNYFWQQ VLDPAWHLLF DGCNLTRESW KALERASFSK LKLQHIQAPL SWELVRPHIY GYAVK; Positive Samples: 22Rv1; Cellular Location: Endoplasmic reticulum, Lipid droplet, Membrane
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: methyltransferase like 7A; methyltransferase like 7A-like; methyltransferase-like protein 7A
基因别名: 2210414H16Rik; 3300001H21Rik; Aam-B; Mettl7a; RGD1308407; UbiE1
Entrez Gene ID: (Rat) 315306, (Mouse) 70152