Invitrogen

MFN1 Polyclonal Antibody

Name: MFN1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-67905
Availability: InStock

2 篇参考文献

查看其他33个MFN1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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MFN1 Antibody (PA5-67905) in WB

Western Blot analysis of MFN1 was performed using lysates from HCT116 cells. The membrane was probed with MFN1 Polyclonal Antibody (Product # PA5-67905) using a dilution of 1:1,000 (4°C).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image MFN1 Polyclonal Antibody

产品信息

PA5-67905

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from human MFN1.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2691921

产品详细信息

Predicted to react with Mouse and Rat samples.

靶标信息

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

仅用于科研。不用于诊断过程。未经明确授权不得转售。