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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
基因别名: MFNG
UniProt ID: (Human) O00587
Entrez Gene ID: (Human) 4242
分子生物学功能: glycosyltransferase