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This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
A suggested positive control is rat lung tissue lysate.
PA5-21049 can be used with blocking peptide PEP-1163.
Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HsMFSD2A; major facilitator superfamily domain containing 2; Major facilitator superfamily domain-containing protein 2A; Mfsd2a; NLS1; sodium-dependent LPC symporter 1; Sodium-dependent lysophosphatidylcholine symporter 1; zgc:101615
基因别名: 1700018O18Rik; HMFN0656; MCPH15; MFSD2; MFSD2A; NLS1; PP9177; RGD1310174; UNQ300/PRO341
UniProt ID: (Human) Q8NA29, (Mouse) Q9DA75
Entrez Gene ID: (Human) 84879, (Rat) 298504, (Mouse) 76574