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MFSD2B Polyclonal Antibody
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Product Details
600-401-CU2
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-MFSD2B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human MFSD2B.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hMfsd2b; major facilitator superfamily domain containing 2B; Major facilitator superfamily domain-containing protein 2B; S1P transporter; sphingosine 1-phosphate transporter; Sphingosine-1-phosphate transporter MFSD2B
Gene Aliases: MFSD2B; RGD1561716; SLC59A2
UniProt ID: (Human) A6NFX1
Entrez Gene ID: (Human) 388931, (Rat) 500624
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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