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Abnova
MGRN1 Monoclonal Antibody (3E1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00023295-M07
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E1
抗原
MGRN1 (NP_056061, 477 a.a. approximately 576 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: PPPLGGAELA LRESSSPESF ITEEVDESSS PQQGTRAASI ENVLQDSSPE HCGRGPPADI YLPGRPTSME TAHGLATTSP TWPPLGGPSP DPSAAELTPL
靶标信息
Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: mahogunin ring finger 1, E3 ubiquitin protein ligase; mahogunin RING finger protein 1; probable E3 ubiquitin-protein ligase MGRN1; putative E-3 ligase; RING finger protein 156; RING-type E3 ubiquitin transferase MGRN1; unnamed protein product
基因别名: RNF156
UniProt ID: (Human) O60291
Entrez Gene ID: (Human) 23295
protein monoubiquitination
smoothened signaling pathway
endosome to lysosome transport
protein ubiquitination
positive regulation of appetite
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of smoothened signaling pathway
negative regulation of melanin biosynthetic process
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
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