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Invitrogen
MICA/MICB (IPH4301 Biosimilar) Recombinant Human Monoclonal Antibody (IPH4301)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-54913
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
IPH4301
抗原
Recombinant Human MICA/MICB.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Compatible with Direct ELISA
靶标信息
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell stress-regulated membrane protein; HLA class I antigen; ligand to the NKG2D receptor; major histocompatibility complex class I chain-related protein A; MHC class I antigen-related protein B; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I related chain A; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; sMICA; sMICB; soluble MICA; soluble MICB; stress inducible class I homolog; unnamed protein product
基因别名: MIC-A; PERB11.1; PERB11.2
UniProt ID: (Human) Q29983, (Human) Q29980
Entrez Gene ID: (Human) 100507436, (Human) 4277
T cell mediated cytotoxicity
immune response to tumor cell
immune response
cellular response to DNA damage stimulus
signal transduction
response to heat
negative regulation of defense response
negative regulation of natural killer cell activation
natural killer cell mediated cytotoxicity
defense response to bacterium
negative regulation of natural killer cell mediated cytotoxicity
gamma-delta T cell activation
regulation of immune response
defense response to virus
immune response-activating cell surface receptor signaling pathway
response to oxidative stress
response to retinoic acid
negative regulation of defense response to virus by host
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
