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Invitrogen
MIP-3 alpha Polyclonal Antibody
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图: 1 / 3
MIP-3 alpha Antibody (PA5-114709) in ICC/IF
Immunocytochemistry analysis of MIP-3 alpha in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114709). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114709
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CCL20(Accession P78556), corresponding to amino acid residues C3-L53.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CCL20.
靶标信息
Macrophage Inflammatory Protein-3 alpha (MIP-3alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta chemokine exodus-1; Beta-chemokine exodus-1; C-C motif chemokine 20; CC chemokine LARC; CC chemokine ST38; chemokine (C-C motif) ligand 20; Liver and activation-regulated chemokine; M-MIP-3-alpha; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 α; MIP 3alpha; MIP 3α; MIP-3-alpha; MIP3 a; MIP3 alpha; MIP3 α; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; Small-inducible cytokine A20
基因别名: CCL20; CKb4; Exodus; exodus-1; LARC; MIP-3-alpha; MIP-3[a]; MIP-3A; MIP3A; SCYA20; ST38
UniProt ID: (Human) P78556, (Mouse) O89093
Entrez Gene ID: (Human) 6364, (Mouse) 20297
chemotaxis
inflammatory response
immune response
signal transduction
cell-cell signaling
calcium-mediated signaling
killing of cells of other organism
defense response to bacterium
cell chemotaxis
antimicrobial humoral immune response mediated by antimicrobial peptide
T cell migration
thymocyte migration
positive regulation of T cell migration
positive regulation of interleukin-1 alpha biosynthetic process
positive regulation of nitric-oxide synthase biosynthetic process
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