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Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Myocardial ischemic preconditioning up-regulated protein 1; myocardial ischemic preconditioning upregulated 1; myocardial ischemic preconditioning upregulated 1 ortholog; Zinc finger protein 667
基因别名: A830025F02Rik; Mip1; MIPU1; Zfp667; ZNF667
UniProt ID: (Human) Q5HYK9, (Rat) Q5MYW4, (Mouse) Q2TL60
Entrez Gene ID: (Human) 63934, (Rat) 308326, (Mouse) 384763