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Invitrogen
MMEL1 Recombinant Mouse Monoclonal Antibody (K8U030_18D9)
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MMEL1 Antibody (MA564468) in IHC (P)
Immunohistochemistry (Paraffin) analysis of MMEL1 in formalin-fixed paraffin-embedded testis tissue. Samples were incubated with MMEL1 recombinant monoclonal (Product # MA564468) using a dilution of 1.3 µg/mL at room temperature for 1 hr followed by Poly-peroxidase conjugated goat anti-mouse IgG. Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogeno... View More
产品信息
MA564468
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K8U030_18D9
抗原
Recombinant human MMEL1 (aa 91-770).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TPGCVIAAAR ILQNMDPTTE PCDDFYQFAC GGWLRRHVIP ETNSRYSIFD VLRDELEVIL KAVLENSTAK DRPAVEKART LYRSCMNQSV IEKRGSQPLL DILEVVGGWP VAMDRWNETV GLEWELERQL ALMNSQFNRR VLIDLFIWND DQNSSRHIIY IDQPTLGMPS REYYFNGGSN RKVREAYLQF MVSVATLLRE DANLPRDSCL VQEDMVQVLE LETQLAKATV PQEERHDVIA LYHRMGLEEL QSQFGLKGFN WTLFIQTVLS SVKIKLLPDE EVVVYGIPYL QNLENIIDTY SARTIQNYLV WRLVLDRIGS LSQRFKDTRV NYRKALFGTM VEEVRWRECV GYVNSNMENA VGSLYVREAF PGDSKSMVRE LIDKVRTVFV ETLDELGWMD EESKKKAQEK AMSIREQIGH PDYILEEMNR RLDEEYSNLN FSEDLYFENS LQNLKVGAQR SLRKLREKVD PNLWIIGAAV VNAFYSPNRN QIVFPAGILQ PPFFSKEQPQ ALNFGGIGMV IGHEITHGFD DNGRNFDKNG NMMDWWSNFS TQHFREQSEC MIYQYGNYSW DLADEQNVNG FNTLGENIAD NGGVRQAYKA YLKWMAEGGK DQQLPGLDLT HEQLFFINYA QVWCGSYRPE FAIQSIKTDV HSPLKYRVLG SLQNLAAFAD TFHCARGTPM
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%, Pig - 86%, Cynomolgus monkey - 98%.
靶标信息
MMEL1 is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. MMEL1 is a type II transmembrane protein and is thought to be expressed as a secreted protein. The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.24; EC 3.4.24.11; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; MGC119454; MGC119455; MGC119456; NEP-like 2; zinc metallopeptidase; NEP2; NEP2(m); NEPII; NEPIIMGC119456; Neprilysin II; Neprilysin-2; NL2NL1; soluble secreted endopeptidase; unnamed protein product; zinc metallopeptidase
基因别名: MELL1; MMEL1; MMEL2; NEP2; NEPII; NL1; NL2; SEP
UniProt ID: (Human) Q495T6
Entrez Gene ID: (Human) 79258
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