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Recommended positive controls: HepG2, human MMP10-transfected 293T, HepG2 conditioned medium.
Predicted reactivity: Mouse (83%), Rat (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: matrix metallo protease; matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP; MMP-10; MMPs; SL-2; stromelysin 2; Stromelysin-2; transin 2; Transin-2
基因别名: MMP10; SL-2; STMY2
UniProt ID: (Human) P09238
Entrez Gene ID: (Human) 4319