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Invitrogen
MMP23 (Cleaved Tyr79) Polyclonal Antibody
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MMP23 (Cleaved Tyr79) Antibody (PA5-37434) in WB
Western blot analysis of MMP23 (Cleaved Tyr79) in Lane 1: HEK293T whole cell lysate (40 µg), Lane 2: HeLa whole cell lysate (40 µg), Lane 3: the Brain tissue lysate of mouse (40 µg), Lane 4: the Brain tissue lysate of rat (40 µg). Samples were incubated with MMP23 (Cleaved Tyr79) polyclonal antibody (Product # PA5-37434) at a dilution of 1:500.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-37434
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 51-100 of human MMP-23
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous protein at a molecular weight of 37 and 44 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MMP 23; MMP23; soluble form
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