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Invitrogen
MMP7 Polyclonal Antibody
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产品信息
PA5-79686
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived mouse MMP7 recombinant protein (Position: Y95-L264).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue. IHC: mouse kidney tissue, rat intestines tissue.
靶标信息
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGNC:7174; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; Uterine metalloproteinase
基因别名: MAT; Mmp-7; Mmp7; MPMM
UniProt ID: (Rat) P50280
Entrez Gene ID: (Rat) 25335, (Mouse) 17393
antibacterial peptide secretion
antibacterial peptide biosynthetic process
proteolysis
aging
collagen catabolic process
response to nutrient levels
regulation of cell proliferation
response to drug
defense response to bacterium
estrous cycle
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
maternal process involved in female pregnancy
cellular response to mechanical stimulus
