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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Positive Samples: HT-29; Cellular Location: extracellular matrix, extracellular space
Immunogen sequence: VPDVAEYSLF PNSPK
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HGNC:7174; Matrilysin; Matrin; matrix metallo protease; matrix metallopeptidase 7 (matrilysin, uterine); Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; uterine matrilysin; Uterine metalloproteinase
基因别名: MMP-7; MMP7; MPMM; MPSL1; PUMP-1; PUMP1
UniProt ID: (Human) P09237, (Rat) P50280
Entrez Gene ID: (Human) 4316, (Rat) 25335
分子生物学功能: metalloprotease