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Invitrogen
MMP7 Monoclonal Antibody (ID2)
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MMP7 Antibody (MA5-14215) in IHC
Biomedicines 2021 -
Figure 1 Representative examples of immunohistochemical staining for MMP-7, MMP-14 and TIMP-1 in colonic mucosa of patients depending on the group of study. 100x magnification for ( a - c , g - l , p - r ). 200x magnification for ( d - f , m - o ). The counterstaining was made with hematoxylin. Arrows indicate cell types: red, cancer cells; blue, epithelial cells; green, mononuclear inflammatory cells; and ... View More
产品信息
MA5-14215
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Rat,
Sheep
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
ID2
抗原
Recombinant human matrilysin (PUMP-1)
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-14215 targets MMP-7 (Matrilysin) in IF applications and shows reactivity with Human samples.
The MA5-14215 immunogen is recombinant human matrilysin (PUMP-1).
靶标信息
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
