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Antibody detects endogenous levels of total MNT.
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHd3; Class D basic helix-loop-helix protein 3; MAX binding protein; Max-binding protein MNT; Max-interacting protein; MNT, MAX dimerization protein; Myc antagonist MNT; Protein ROX
基因别名: BHLHD3; MAD6; MNT; MXD6; ROX
UniProt ID: (Human) Q99583
Entrez Gene ID: (Human) 4335