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Invitrogen
MOZ Recombinant Rabbit Monoclonal Antibody (PSH09-88)
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MOZ Antibody (MA570102) in ICC/IF
Immunocytochemistry analysis of MOZ in Huh7 cells. Samples were incubated with MOZ monoclonal antibody (Product # MA570102) using a dilution of 1:500 in 1% BSA in PBST overnight at 4°C followed by Goat Anti-Rabbit IgG H&L (iFluor™ 488) at a dilution of 1:1,000. Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. PBS instead of the primary antibody was use... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA570102
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH09-88
抗原
Recombinant protein within human KAT6A aa 785-1,034.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Huh7, human liver tissue, human placenta tissue, mouse liver tissue, mouse placenta tissue, rat liver tissue.
Subcellular location: Nucleus, nucleolus, nucleoplasm, PML body.
靶标信息
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: histone acetyltransferase MYST3; K(lysine) acetyltransferase 6A; monocytic leukemia zinc finger homolog; monocytic leukemia zinc finger protein; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST protein 3; MYST-3; runt-related transcription factor binding protein 2; unnamed protein product; zinc finger protein 220
基因别名: 1500036M03; 9930021N24Rik; ARTHS; MOZ; MRD32; MYST-3; MYST3; RUNXBP2; ZC2HC6A; Zfp220; ZNF220
UniProt ID: (Human) Q92794, (Rat) Q5TKR9
Entrez Gene ID: (Human) 7994, (Rat) 306571, (Mouse) 244349
DNA binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
histone acetyltransferase activity
protein binding
zinc ion binding
H3 histone acetyltransferase activity
acetyltransferase activity
histone acetyltransferase activity (H3-K14 specific)
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K12 specific)
histone acetyltransferase activity (H4-K16 specific)
peptide-lysine-N-acetyltransferase activity
DNA-binding transcription factor binding
histone acetyltransferase activity (H3-K9 specific)
nucleosome assembly
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of gene expression
myeloid cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
regulation of developmental process
chromosome organization
cellular senescence
regulation of signal transduction by p53 class mediator
regulation of hemopoiesis
heart morphogenesis
somatic stem cell population maintenance
embryonic hemopoiesis
aorta morphogenesis
face morphogenesis
protein acetylation
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