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Bethyl Laboratories
MPP5/Pals1 Polyclonal Antibody
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MPP5/Pals1 Antibody (A305-389A) in WB
Detection of human MPP5 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-MPP5 antibody (Product # A305-389A) (lot A305-389A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
产品信息
A305-389A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 600 to 650 of human MAGUK p55 subfamily member 5.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
靶标信息
MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons. It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells. Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells. MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ12615; MAGUK p55 subfamily member 5; Membrane protein, palmitoylated 5; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); palmitoylated 5; protein associated with lin seven 1; Protein associated with Lin-7 1; Protein PALS1; stardust
基因别名: MPP5; PALS1
UniProt ID: (Human) Q8N3R9
Entrez Gene ID: (Human) 64398
