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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: NSKRDYTGCST SESLSPVKQA PRKSPSDTEG LVKSLPSGSH QGPVIYAQLD HSGGHHSDKI NKSESVVYAD IRKN
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ21047; Myelin protein zero-like protein 1; Protein zero-related
Gene Aliases: MPZL1; PZR; UNQ849/PRO1787
Entrez Gene ID: (Human) 9019
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