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Invitrogen
MRAP Polyclonal Antibody
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Product Details
PA5-52775
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MRAP. Recombinant protein control fragment (Product #RP-90458).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MANGTNASAP YYSYEYYLDY LDLIPVDEKK LKAHKHS
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 81%.
Target Information
MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B27; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; Melanocortin-2 receptor accessory protein; membrane protein expressed in adipocytes; membrane protein; expressed in fat cells
Gene Aliases: B27; C21orf61; FALP; FGD2; GCCD2; MRAP; MRAP1
UniProt ID: (Human) Q8TCY5
Entrez Gene ID: (Human) 56246
protein localization to plasma membrane
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
negative regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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