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Invitrogen
MRCK gamma Polyclonal Antibody
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产品信息
PA5-55595
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PSNSLIPFLS FRSSEKDSAK DPGISGEATR HGGEPDLRPE GRRSLRMGAV FPRAPTANTA STEGLPAKPG SH
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 71%.
靶标信息
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC42 binding protein kinase gamma (DMPK-like); CDC42-binding protein kinase gamma; CDC42BPG; DMPK-like gamma; MRCK gamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase like protein; Myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; Serine/threonine-protein kinase MRCK gamma
基因别名: CDC42BPG; DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma
UniProt ID: (Human) Q6DT37
Entrez Gene ID: (Human) 55561
