Invitrogen

MRP4 Polyclonal Antibody

Name: MRP4 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-120801

查看其他22个MRP4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

MRP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 5

MRP4 Antibody (PA5-120801) in IHC (P)

Immunohistochemistry analysis of MRP4 in paraffin-embedded human prostate cancer. Samples were incubated with MRP4 Polyclonal antibody (Product # PA5-120801) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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Immunogen image

Immunogen Image MRP4 Polyclonal Antibody

产品信息

PA5-120801

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

Assay-dependent

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 1067-1325 of human MRP4/ABCC4 (NP_005836.2).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2914373

产品详细信息

Positive test controls include: HeLa, HeLa Cytoplasm extracts, 293T. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.

Immunogen sequence: SQEKVGIVGR TGAGKSSLIS ALFRLSEPEG KIWIDKILTT EIGLHDLRKK MSIIPQEPVL FTGTMRKNLD PFNEHTDEEL WNALQEVQLK ETIEDLPGKM DTELAESGSN FSVGQRQLVC LARAILRKNQ ILIIDEATAN VDPRTDELIQ KKIREKFAHC TVLTIAHRLN TIIDSDKIMV LDSGRLKEYD EPYVLLQNKE SLFYKMVQQL GKAEAAALTE TAKQVYFKRN YPHIGHTDHM VTNTSNGQPS TLTIFETAL

靶标信息

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ABC-tranporter; ATP-binding cassette protein C4; ATP-binding cassette sub-family C member 4; ATP-binding cassette subfamily C member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MOAT-B; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; Multidrug resistance-associated protein 4; RP11-74A12.1

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基因别名: ABCC4; D630049P08Rik; MOAT-B; MOATB; MRP4

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UniProt ID: (Human) O15439, (Rat) F1M3J4, (Mouse) E9Q236

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Entrez Gene ID: (Human) 10257, (Rat) 170924, (Mouse) 239273

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功能

ATP binding ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 15-hydroxyprostaglandin dehydrogenase (NAD+) activity anion transmembrane-transporting ATPase activity molecular_function ATPase activity, coupled to transmembrane movement of substances drug transmembrane transporter activity ATP-binding cassette (ABC) transporter

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