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Invitrogen
MRPL11 Monoclonal Antibody (24GB13260)
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MRPL11 Antibody (MA570811) in ICC/IF
Immunocytochemistry analysis of MRPL11 in HepG2 cells. Sample was incubated with MRPL11 monoclonal antibody (Product # MA570811) at a dilution of 1:1,000. Nuclei were stained blue with DAPI and Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 μm.
产品信息
MA570811
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
24GB13260
抗原
Recombinant protein of human (1-192) MRPL11.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39S ribosomal protein L11, mitochondrial; cgi-113 protein; L11mt; Large ribosomal subunit protein uL11m; mgc111024; MRP-L11
基因别名: 2410001P07Rik; CGI-113; L11MT; MRP-L11; MRPL11
UniProt ID: (Human) Q9Y3B7, (Mouse) Q9CQF0, (Rat) Q5XIE3
Entrez Gene ID: (Human) 65003, (Mouse) 66419, (Rat) 293666
