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Invitrogen
MTHFR Recombinant Rabbit Monoclonal Antibody (4Y4B9)
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图: 1 / 4
MTHFR Antibody (MA569220) in ICC/IF
Immunocytochemical analysis of MTHFR in HT-29 cells. Samples were incubated with MTHFR recombinant monoclonal antibody (Product # MA569220) using a dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) using a dilution of 1:500. DAPI for nuclear staining (Blue).
产品信息
MA569220
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4Y4B9
抗原
Recombinant protein (or fragment).
偶联物
形式
Liquid
浓度
1.86 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3., with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5,10-methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); Methylenetetrahydrofolate reductase (NADPH); MTHFR; MTHFR long isoform; MTHFR short isoform; RP11-56N19.4; unnamed protein product
基因别名: AI323986; MTHFR
UniProt ID: (Human) P42898, (Mouse) Q9WU20
Entrez Gene ID: (Human) 4524, (Rat) 362657, (Mouse) 17769
catalytic activity
methylenetetrahydrofolate reductase (NAD(P)H) activity
protein binding
oxidoreductase activity
macromolecular complex binding
flavin adenine dinucleotide binding
NADP binding
FAD binding
modified amino acid binding
methylenetetrahydrofolate reductase (NADPH) activity
protein complex binding
reductase
oxidoreductase
metabolite interconversion enzyme
response to hypoxia
neural tube closure
methionine metabolic process
methionine biosynthetic process
response to xenobiotic stimulus
response to vitamin B2
tetrahydrofolate interconversion
response to amino acid
S-adenosylmethionine metabolic process
tetrahydrofolate metabolic process
homocysteine metabolic process
response to folic acid
response to interleukin-1
heterochromatin organization
one-carbon metabolic process
response to drug
oxidation-reduction process
metabolic process
regulation of histone methylation
heterochromatin maintenance
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