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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DRTPLFISLL RLSLWADGLI HTSLKPTEIL YLTVAYDWFL FGHMLVDRLS KGEEIFFFCF NFLKHITSEE FSALKTQRRK SLPARDGGFT LEDICMLRRK DRGSTTSLGS DFSLVMESSP GATGSFTYEA VELVPAGAPT QAAWRKSHSS SPQSVLWNRP QPSEDR
Positive Samples: BT-474, Jurkat, Mouse liver, Mouse spleen, Mouse testis, Rat brain; Cellular Location: Cytoplasm
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: egg-derived tyrosine phosphatase homolog; jumpy; mJumpy; myotubularin-related protein 14; NS5ATP4ABP1; phosphatidylinositol-3-phosphate phosphatase; unnamed protein product
基因别名: 1110061O04Rik; C3orf29; RGD1304842
UniProt ID: (Human) Q8NCE2, (Mouse) Q8VEL2
Entrez Gene ID: (Human) 64419, (Mouse) 97287, (Rat) 312634