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Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (89%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mel-1B-R; mel1b receptor; melatonin receptor 1B variant b; melatonin receptor MEL1B; Melatonin receptor type 1B
基因别名: FGQTL2; MEL-1B-R; MT2; MTNR1B
UniProt ID: (Human) P49286
Entrez Gene ID: (Human) 4544