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Invitrogen
MUC17 Biosimilar Recombinant Human Monoclonal Antibody
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产品信息
MA5-59349
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term Forerunner patent anti-Muc 17.
靶标信息
MUC17, a member of the mucin family of glycosylated proteins, is located in the q22.1 region of chromosome 7, specifically between the MUC12 and SERPINE1 genes. The MUC17 gene spans a 39-kb DNA fragment and contains 13 exons, producing a 14.2-kb mRNA. MUC17 is characterized by the generation of two splice variants that encode either a membrane-anchored or a secreted form. This gene plays a crucial role in epithelial cell protection and renewal, primarily in the gastrointestinal tract. MUC17's large extracellular domain, which includes tandem repeat regions, is extensively glycosylated, contributing to the formation of a protective mucous barrier.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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