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Invitrogen
MUM1L1 Polyclonal Antibody
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产品信息
PA5-51360
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KVALGILNER TNLSQASTSD EEEITMLSQN VPQKQSDSPP HKKYRKDEGD LPGCLEEREN SACLLASSES DDSLYDDKSQ APTMVDTIPS EVETKSLQNS SWCETFPSLS E
Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 50%.
靶标信息
The MUM1L1 (Melanoma Associated Antigen (Mutated) 1-Like 1) gene encodes a protein that is a member of the PWWP domain-containing family and is thought to be involved in chromatin organization and gene expression regulation. Located on chromosome Xq22.3, MUM1L1 shares homology with the oncogene MUM1, known for its roles in cancer biology, particularly in multiple myeloma and lymphomas. The PWWP domain of MUM1L1 is implicated in binding histone methylation marks, thereby influencing transcriptional activity. Although the precise biological function of MUM1L1 remains to be fully elucidated, its expression patterns suggest a role in cell proliferation and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: melanoma associated antigen (mutated) 1-like 1; MUM1-like protein 1; Mutated melanoma-associated antigen 1-like protein 1; PWWP domain-containing DNA repair factor 3B; PWWP domain-containing protein MUM1L1; PWWP3B
基因别名: MUM1L1; PWWP3B
UniProt ID: (Human) Q5H9M0
Entrez Gene ID: (Human) 139221
