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Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-protein, cardiac muscle isoform; cardiac C-protein; cardiac MyBP-C; DKFZp779E1762; myosin-binding protein C, cardiac-type
Entrez Gene ID: (Mouse) 17868