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Invitrogen
MYCT1 Polyclonal Antibody
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产品信息
PA5-109999
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 99-235 of human MYCT1 (NP_079383.2).
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ASAPISQWSS SRRSRSSYTH GLNRTGFYRH SGCERRSNLS LASLTFQRQA SLEQANSFPR KSSFRASTFH PFLQCPPLPV ETESQLVTLP SSNISPTIST SHSLSRPDYW SSNSLRVGLS TPPPPAYESI IKAFPDS
靶标信息
MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MT-MC1; myc target in myeloid cells 1; Myc target in myeloid cells protein 1; Myc target protein 1
基因别名: 1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MYCT1
UniProt ID: (Human) Q8N699, (Mouse) Q8R411
Entrez Gene ID: (Human) 80177, (Mouse) 68632, (Rat) 292264
