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Invitrogen
MYL2 Polyclonal Antibody
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Product Details
PA5-54073
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYL2. Recombinant protein control fragment (Product #RP-89522).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GPINFTVFLT MFGEKLKGAD PEETILNAFK VFDPEGKGVL KADYVREMLT TQAERFSKEE VDQMFAAFPP DVTGNLDYKN LVHIITHGE
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 82%.
Target Information
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cardiac myosin light chain 2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain phosphatase; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2
Gene Aliases: CMH10; MLC-2s/v; MLC2; MYL2
UniProt ID: (Human) P10916
Entrez Gene ID: (Human) 4633
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
post-embryonic development
muscle filament sliding
negative regulation of cell growth
muscle cell fate specification
muscle fiber development
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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