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Invitrogen
MYLK2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50236
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to residues near the C terminal of human myosin light chain kinase 2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total MYLK2 protein.
Target Information
MYLK2 (skMLCK) is a calcium/calmodulin-dependent serine/threonine kinase expressed exclusively in adult skeletal muscle. MYLK2 encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MLCK2; Myosin light chain kinase 2, skeletal/cardiac muscle
Gene Aliases: 9830004H17Rik; BB138278; MYLK2
UniProt ID: (Mouse) Q8VCR8
Entrez Gene ID: (Mouse) 228785
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
myosin light chain kinase activity
protein binding
calmodulin binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
myosin light chain binding
non-receptor serine/threonine protein kinase
protein phosphorylation
water transport
regulation of muscle contraction
striated muscle contraction
neuromuscular synaptic transmission
positive regulation of gene expression
skeletal muscle satellite cell differentiation
phosphorylation
peptidyl-threonine phosphorylation
positive regulation of fast-twitch skeletal muscle fiber contraction
regulation of muscle filament sliding
skeletal muscle cell differentiation
regulation of MAPK cascade
protein autophosphorylation
regulation of neuronal synaptic plasticity
synaptic vesicle transport
regulation of cell cycle
cardiac muscle cell differentiation
cardiac muscle tissue morphogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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