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Invitrogen
MYOCD Polyclonal Antibody
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图: 1 / 13
MYOCD Antibody (PA5-100775) in ICC/IF
Immunocytochemistry analysis of MYOCD in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MYOCD polyclonal antibody (Product # PA5-100775) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100775
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MYOCD(Accession Q8IZQ8), corresponding to amino acid residues G221-P271.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MYOCD.
靶标信息
Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: basic SAP coiled-coil transcription activator 2; MYOCD-B; transcription factor; SRF-binding; SRF co-factor protein (cardiac and smooth muscle); SRF cofactor protein; transcription factor; transcription factor myocardin; transcriptional cofactor for serum response factor; unnamed protein product
基因别名: BSAC2A; MGBL; MYCD; Srfcp
UniProt ID: (Human) Q8IZQ8, (Rat) Q8R5I7, (Mouse) Q8VIM5
Entrez Gene ID: (Human) 93649, (Rat) 246297, (Mouse) 214384
response to hypoxia
heart development
negative regulation of cell proliferation
positive regulation of gene expression
positive regulation of transforming growth factor beta receptor signaling pathway
cardiocyte differentiation
vascular smooth muscle cell differentiation
positive regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
smooth muscle cell differentiation
regulation of muscle cell differentiation
regulation of smooth muscle cell differentiation
positive regulation of smooth muscle cell differentiation
cardiac muscle cell differentiation
urinary bladder development
cardiac muscle cell myoblast differentiation
cardiac vascular smooth muscle cell differentiation
negative regulation of beta-amyloid clearance
regulation of phenotypic switching
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration
negative regulation of platelet-derived growth factor receptor-beta signaling pathway
positive regulation of cardiac muscle cell differentiation
negative regulation of skeletal muscle cell differentiation
negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth by extracellular stimulus
vasculogenesis
cardiac ventricle development
chromatin organization
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
response to mechanical stimulus
positive regulation of cardiac muscle hypertrophy
negative regulation of cardiac muscle cell apoptotic process
positive regulation of epithelial to mesenchymal transition
negative regulation of myotube differentiation
hepatic stellate cell activation
response to muscle stretch
muscle cell differentiation
regulation of myoblast differentiation
lung alveolus development
digestive tract development
ventricular cardiac muscle cell differentiation
uterus development
negative regulation of cell adhesion molecule production
cell growth involved in cardiac muscle cell development
cellular response to growth factor stimulus
cellular response to hypoxia
cellular response to transforming growth factor beta stimulus
ductus arteriosus closure
cellular response to angiotensin
regulation of vascular associated smooth muscle cell migration
positive regulation of vascular associated smooth muscle cell migration
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