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Invitrogen

MYST2 Polyclonal Antibody

View all (19) MYST2 antibodies

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Product Details

PA5-27601

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human MYST2. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 1% BSA, 20% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2545077

Product Specific Information

Recommended positive controls: NT2D1, IMR32, MCF-7, mouse brain.

Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (90%), Pig (99%), Bovine (99%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EC 2.3.1.48; HBO1; Histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K(lysine) acetyltransferase 7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST family member; MYST histone acetyltransferase 2; MYST-2; unnamed protein product

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Gene Aliases: HBO1; HBOA; KAT7; MYST2; ZC2HC7

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UniProt ID: (Human) O95251, (Mouse) Q5SVQ0

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Entrez Gene ID: (Human) 11143, (Mouse) 217127

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Function(s)
chromatin binding DNA replication origin binding transcription cofactor activity histone acetyltransferase activity protein binding zinc ion binding H3 histone acetyltransferase activity H4 histone acetyltransferase activity transferase activity transferase activity, transferring acyl groups histone acetyltransferase activity (H3-K14 specific) histone acetyltransferase activity (H3-K23 specific) histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K12 specific) histone acetyltransferase activity (H3-K4 specific) metal ion binding histone acetyltransferase activity (H4-K16 specific) transcription factor activity, sequence-specific DNA binding transferase activity, transferring acyl groups other than amino-acyl groups histone modifying enzyme
Process(es)
regulation of cell growth natural killer cell differentiation DNA replication regulation of DNA replication DNA repair chromatin organization regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter cellular response to DNA damage stimulus internal peptidyl-lysine acetylation regulation of DNA-dependent DNA replication initiation T cell differentiation stress-activated protein kinase signaling cascade positive regulation of DNA-templated transcription, elongation positive regulation of erythrocyte differentiation positive regulation of DNA replication positive regulation of gene expression, epigenetic positive regulation of nucleobase-containing compound metabolic process positive regulation of transcription from RNA polymerase II promoter regulation of cell cycle response to sorbitol response to hydroxyurea response to actinomycin D response to dithiothreitol response to anisomycin DNA replication-dependent chromatin disassembly positive regulation of protein localization to nucleus positive regulation of hematopoietic stem cell proliferation regulation of DNA biosynthetic process regulation of nucleotide-excision repair transcription, DNA-templated chromatin modification histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation
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