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Recommended positive controls: Molt-4, Raji.
Predicted reactivity: Rhesus Monkey (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: caspase-2 binding protein; HSPC190; marginal zone B and B1 cell-specific protein; Marginal zone B- and B1-cell-specific protein; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
基因别名: 2010001M09Rik; AV064572; HSPC190; MEDA-7; MEDA7; MZB1; PACAP; pERp1
UniProt ID: (Human) Q8WU39, (Mouse) Q9D8I1
Entrez Gene ID: (Human) 51237, (Mouse) 69816