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Invitrogen
Medroxyprogesterone Recombinant Mouse Monoclonal Antibody (3E11)
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Medroxyprogesterone Antibody (MA566426) in SDS-PAGE
SDS-PAGE characterization of Medroxyprogesterone under reducing conditions. Lane M: Protein marker (kDa); Lane MP: Purified Medroxyprogesterone Recombinant Monoclonal (Product # MA566426). Medroxyprogesterone showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-369.
产品信息
MA566426
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3E11
抗原
Conjugate of MP hapten and KLH.
偶联物
形式
Liquid
浓度
7.1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Medroxyprogesterone acetate (MPA) is a synthetic progestin commonly used in hormone replacement therapy and contraceptive formulations. It is a derivative of progesterone, with modifications that enhance its stability and bioavailability. MPA functions as a progesterone agonist, exerting its effects by binding to progesterone receptors in target tissues, which leads to changes in gene expression and cellular activity. It is primarily used to regulate menstrual cycles, treat endometriosis, and as part of hormone replacement therapy for menopausal symptoms. The gene location and structure of medroxyprogesterone are not directly applicable as it is a synthetic compound rather than a naturally occurring gene product. However, its mechanism of action involves interaction with the progesterone receptor gene, influencing reproductive tissue function. Studies have shown that MPA can induce apoptosis in human endometrial endothelial cells, highlighting its role in modulating cellular processes. Synonyms for medroxyprogesterone include medroxyprogesterone acetate, MPA, Provera, Depo-Provera, Amen, Curretab, Cycrin, and Depo-SubQ Provera 104.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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