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Invitrogen
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Compatible with Direct ELISA
Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear. [National Center for Biotechnology Information. PubChem Compound Database; CID=126941].
仅用于科研。不用于诊断过程。未经明确授权不得转售。